The processes of Meiosis 1 and Meiosis 2 have key parts that contribute to each process being different. One key difference is that neither cell of meiosis 2 goes through chromosome replication.While in meiosis one the cell does go through this process. Another difference is that in meiosis 1 the chromosomes line up individually across the cell. In meiosis 2 they just line up in the center. The final example is that meiosis 1 separates homologous chromosomes while meiosis 2 separates sister chromatids. In, conclusion the processes of meiosis 1 and meiosis 2 have key differences.